Written by Alexander E. Berezin
Published On Issue 2 Vol 11, 2020
Klotho protein is a powerful regulator of various metabolic pathways including endothelial integration, cell adaptation processes, ion transport, signal transduction, regulation of calcium, potassium, parathyroid hormone, phosphates and glucose metabolism, and reduction of oxidative stress. Klotho protein ensures its biological effects through binding with fibroblast growth factor (FGF)-23 and altered Klotho/FGF23 axis was found a core element in the pathogenesis of the cardiovascular and metabo
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Written by Rasha A. Mansouri
Published On Issue 2 Vol 11, 2020
This study aimed to evaluate the antioxidant activity of punicalagin, which is extracted from the pomegranate, on the stability of olive oil in comparison with butylated hydroxytoluene (BHT). The evaluation was carried out by measuring peroxide value (PV) and acid value (AV) to identify the primary products of oil oxidation. Thiobarbituric acid reactive substances (TBARS) and P-Ansidine value (PAV) were used to identify the secondary products of oxidation. Also, the total oxidation index (TOTOX)
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Written by Anurag Jyoti
Published On Issue 2 Vol 11, 2020
Safe drinking water in an urban city has been a great challenge for the human population. Consumption of contaminated water may lead to the occurrence of several diseases. Enterotoxigenic Escherichia coli (ETEC) is an enteric pathogen that can survive even in treated drinking water and cause watery diarrhea. The pathogen harbors virulent and drug-resistant genes responsible for its virulence and antibiotic resistance. Persistence of such strains of ETEC is often associated with disease outbreaks
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Written by Eman Hassan Ahmed Algarni
Published On Issue 2 Vol 11, 2020
Bioactive compounds are important to be worthy of attention to human nutrition and useful to health also as they prevent the process of developing of more diseases. Therefore the aim of this study to evaluate the pumpkin flour and its blends as sponge cake and pancake were separately prepared at different levels 5.0, 10.0, 15.0, and 20%, respectively, compared with the control sponge cake and pancake made from wheat flour 72% extraction. The results indicated that the pumpkin flour had contained
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Written by Sulukhan Temirbekova
Published On Issue 2 Vol 11, 2020
Safflower was introduced into the Central region of the Russian Federation. The results of many years of research have a fundamental and applied significance. Vegetation period from germination to maturity in the years with different meteorological conditions is 94-114 days. The weight of 1000 seeds is 48-51 g. Productivity in contrast zone is 0.7-1.7 t/ha. Safflower seeds contain 30.2-30.9% of fat, the yield of oil is 240 liters kg/ha (in unrefined seeds). From diseases during the wet years of
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Written by Heba A. Sindi
Published On Issue 2 Vol 11, 2020
The Kingdom of Saudi Arabia is one of the countries in the Middle East burdened with type 2 diabetes (T2D). This type of diabetes is associated with an increase in the body's resistance to insulin action. Elevated blood pressure is one of the most important diseases that accompany T2D. Many experimental and clinical studies have shown the effectiveness of olive leaves extract (OLEx) in controlling T2D, as well as hypertension. This review aimed to collect clinical studies conducted in humans
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Written by Noureddine Tamma
Published On Issue 2 Vol 11, 2020
The Objective: The aim of this study was to analyze the qualitative and quantitative phytochemicals, assess the properties of antibacterial in the laboratory and identify biologically active compounds in extracts Citrullus Colocythis Collected from ElOued in the region Hassani and Hamraya. Method : A quantitative, quantitative, and in vitro quantitative qualitative analysis was performed using standard procedures. Biologically active compounds were analyzed. Results: Through the results, we dedu
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Written by Aysha A. Alshareef and Maha Ibrahim
Published On Issue 2 Vol 11, 2020
Petroleum, or what is known among the general public as benzene, contains monocyclic aromatic hydrocarbon compounds. Benzene may contain lead or be lead-free. There are few studies that have examined the toxic effects of inhaling benzene fumes on experimental animals. This study aimed to investigate the sub-acute toxicity of inhaling benzene vapor in experimental rats. The rats were exposed to benzene vapors for 1, 2, and 4 hours daily for 5 days per week. The experiment lasted for 3 weeks. Benz
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Written by Samara M.
Published On Issue 2 Vol 11, 2020
The aim is to study the clinical profiles of patients with severe AP treated surgically during their stay in the hospital. Methods and materials: a result analysis of treating 125 patients with severe forms of acute pancreatitis was carried out. All patients in the preoperative period were imaged through ultrasound scanning (hereinafter referred to as the US). 40 patients were also imaged through computed tomography (hereinafter referred to as CT). US and CT data obtained before surgery were com
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Written by Heshmat Allah Ebrahimi Shahraki
Published On Issue 2 Vol 11, 2020
A good apical seal is one of the criteria for the success of the endodontic treatment. The ‎most common causes of failure in endodontic treatment are referred to the lack of proper ‎apical seal. The aim of this in vitro study was to evaluate the apical sealing ability where the ‎canals were prepared by wave one and recipro systems.‎ Material & Method‏:‏ Fifty one extracted human teeth with single root were divided randomly into 3 similar ‎groups of fifteen of each
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Written by Aysha A. Alshareef
Published On Issue 2 Vol 11, 2020
Exposure to benzene vapor boosts diverse and serious health dangers. Benzene station workers are particularly susceptible to benzene inspiration toxicity. This study aimed to investigate the probable neurological, hematological, nephrotoxicity, and hepatotoxicity of benzene inhalation in benzene station workers. This study is a retrospective, cross-sectional study, conducted on 29 benzene station workers (benzene exposed subjects) and 11 control subjects (benzene unexposed subjects). The partici
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Written by Hisham Ali Waggiallah
Published On Issue 2 Vol 11, 2020
Erythrocyte damage such as osmotic shock, oxidative stress, or energy depletion promotes the generation of prostaglandin E2 by activating cyclooxygenase, which triggers a permeable Ca+2 cation channel. Ca+2 further promotes the transfer of Phosphatidylserine from the cell membrane inside to the outer by a scramblase. Macrophages recognize phosphatidylserine at the surface of the erythrocyte which engulfs and degrade the affected cells. Also, the revealing phosphatidylserine red cell may bind to
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Written by Nguyen Tri
Published On Issue 2 Vol 11, 2020
Salmon bones - byproducts in food industries, was regarded as waste and will be discarded without fully utilizing it. From the approach of waste to wealth in the chemical compositions, the by-product can be employed as a cheap bioresource to form nanohydroxyapatite. In this paper, the influence of hydrothermal and calcined conditions on the structure of nano-hydroxyapatite synthesized from the salmon fishbone by the hydrothermal method was investigated. Various techniques such as X-ray diffracti
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Written by Yasir M. Kadhim
Published On Issue 2 Vol 11, 2020
Objective: To synthesize and preliminary pharmacological evaluation of new analogs of several new Schiff bases of diclofenac by investigating their interactions with COX-2 by docking and defining certain associations between their structures to improve selectivity towards COX-2 and to decrease side effects. Methods: Several new diclofenac Schiff bases were designed, prepared, and tested as potential COX-2 inhibitors. These new compounds were tested by molecular docking using genetic optimization
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Written by Lienda Bashier Eltayeb
Published On Issue 2 Vol 11, 2020
Background: Plasmodium falciparum's biodiversity still seems to be argumentative, and hinders malaria control, the current study aimed to characterize P. falciparum isolates for genetic markers polymorphism of (msp-1(k1 and ro33) and (msp-2 (FC27 and 3D7)) among malaria-infected Sudanese children. Methods: A total of 100 blood samples from patients were collected from April to August 2019. Blood films and PCR confirmed P. falciparum mono-infections and following gel electrophores
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Written by Eman S. Ibrahem
Published On Issue 2 Vol 11, 2020
Stevia rebaudianaBertoni (Stevia), is a plant species in the genus Stevia. This study aimed to explore the main active constituents of dried Stevia leaves. Besides, the antimicrobial and cytotoxic properties of 6 Stevia extracts (aqueous, methanol, ethanol, acetone, chloroform, and petroleum ether) were assessed. Stevia leaves were dried by solar energy then the proximal chemical analysis and the total antioxidant capacitywere conducted. The antimicrobial effects of the 6 different solvent extra
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Written by Nikolay Buyankin
Published On Issue 2 Vol 11, 2020
Planting a mixture of grass and legume seeds with different linear growth rates allows one to set multilayer crops where the bottom layer is taken by lupine and millet, and the top one – by beans, vetch, and peas. This distribution allows the plants to maximize their sunlight intake and prevents soil moisture evaporation. Analysis of the rhizospheric indices has made it possible to determine the way soil rhizospheric processes develop in legume crops after the spring and summer plant
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Written by Sulukhan Temirbekova
Published On Issue 2 Vol 11, 2020
Presents the results of a long-term study of spring barley collection samples from the gene pool of VIR. Field experiments were carried out on conventional agricultural techniques. Collection samples seeds were sown in optimal time (I decade of may) on plots of 2 m2. Shoots are obtained on the 10-15th day in different years. The vegetation period of the standard in different years was from 81 to 92 days depending on weather conditions, and collection samples from 65 to 93 days. The harvest
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Written by Hisham Ali Waggiallah
Published On Issue 2 Vol 11, 2020
Hepcidin controls the systemic level of iron as well as the transfer of tissue iron by binding ferroportin to the iron exporter, which allows it to be depleted. Iron is an important element needed by all organisms because of its role in a range of critical cellular biochemical pathways such as DNA production and respiration. Iron is available to both host and pathogen during Mycobacterium tuberculosis (TB) infection. Tuberculosis may have an influence on the contagious result. Both the host and
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Written by Raed A. Alshehri
Published On Issue 2 Vol 11, 2020
Background: Conjunctivitis is a common eye presentation in practice, that can be caused by multiple etiologies that include viruses, bacteria, and allergies. The presentation is composed of conjunctival injection along with itchiness and discharge, among other symptoms. The slight differences between each etiological factor can lead the way to set a satisfactory management plan. Clinical experience is required in dealing with conjunctivitis as it is usually presented in a primary health clinic,
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Written by Alaa A. Alarnaouti
Published On Issue 2 Vol 11, 2020
Background: Celiac disease is not an uncommon condition in the pediatric group. However, the exact mechanism is unknown; however, many hypotheses claim that genetic factors play an essential role. Clinical manifestations could be related to the intestinal such as diarrhea and abdominal pain or extra-intestinal such as anemia or dermatitis herpetiformis. The diagnosis is based on clinical, serological, and intestinal biopsy; however, the gold standard is the biopsy—treatment based on lifest
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