2020 Volume 11 Issue 2
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Probable Toxicity of Benzene Inhalation on Nervous System and Blood Image of Gas Station Workers


Aysha A. Alshareef, Maha Ibrahim
Abstract

Exposure to benzene vapor boosts diverse and serious health dangers. Benzene station workers are particularly susceptible to benzene inspiration toxicity. This study aimed to investigate the probable neurological, hematological, nephrotoxicity, and hepatotoxicity of benzene inhalation in benzene station workers. This study is a retrospective, cross-sectional study, conducted on 29 benzene station workers (benzene exposed subjects) and 11 control subjects (benzene unexposed subjects). The participants included in this study have been chosen from different fuel stations in Jeddah, Saudi Arabia. The average duration for benzene exposure is 12 hours/day. The results of this study showed that the exposure of workers at benzene stations to benzene vapor hurt liver function, especially the AST enzyme, and also reduced the level of dopamine in the plasma of these workers. The current study also showed that no statistical changes occurred in the blood picture count, kidney function (creatinine and urea), and the plasma lipid profile (TC and HDL-C) in the workers who are exposed to inhaling benzene vapor at their workplace. The results of this study concluded that exposure to benzene vapor induced numerous and serious health hazards including elevated liver enzymes as well as reduced dopamine concentration.


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