Background: Celiac disease is not an uncommon condition in the pediatric group. However, the exact mechanism is unknown; however, many hypotheses claim that genetic factors play an essential role. Clinical manifestations could be related to the intestinal such as diarrhea and abdominal pain or extra-intestinal such as anemia or dermatitis herpetiformis. The diagnosis is based on clinical, serological, and intestinal biopsy; however, the gold standard is the biopsy—treatment based on lifestyle modification by a gluten-free diet. Objective: The objective of this review is to discuss Celiac disease in a pediatric, different presentation, diagnosis, and management. Method: We searched the PubMed database looking for relevant articles to the topic using Mesh terms, "Celiac disease." Conclusion: Celiac disease is a common condition in the pediatric age group. The early diagnosis and treatment will not only treat your patient, and rather, it will prevent complications in the child, such as failure to thrive, anemia, and neurological disorder.
