Background: Conjunctivitis is a common eye presentation in practice, that can be caused by multiple etiologies that include viruses, bacteria, and allergies. The presentation is composed of conjunctival injection along with itchiness and discharge, among other symptoms. The slight differences between each etiological factor can lead the way to set a satisfactory management plan. Clinical experience is required in dealing with conjunctivitis as it is usually presented in a primary health clinic, thus knowing the red flags is important. Objectives: We aimed to review the literature looking for etiology of conjunctivitis, risk factors, clinical presentation, diagnosis, management, and possible complications of this disease. Methodology: PubMed database was used for article selection, gathered papers had undergone a thorough review. Conclusion: Conjunctivitis cases must be dealt with with extreme delicacy; as the history and physical examination are the key for appropriate diagnosis rather than laboratory and radiological testing. A holistic approach to treating the patient is the essence of a fruitful management plan. Moreover, patient education along with pharmacological treatment is the optimal solution. The prognosis of conjunctivitis is usually good and adverse complications, almost, limited to neglected cases.