Written by Jehan Abdulwahab Mohammad
Published on Issue 1 Vol 17, 2026
Resistin, a hormone secreted by adipose tissue and immune cells, has a key role in the diagnosis and treatment of many inflammatory and metabolic disorders. However, the precise role of resistin in the human body remains to be studied further. Sixty-seven individuals were involved in this study and divided into 2 groups: 36 patients with stage III periodontitis (case group) and 31 healthy individuals (control group). In addition to their ages, sexes, and body mass index, serum levels of resistin
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Written by Tugolbay Mamaev
Published on Issue 1 Vol 17, 2026
The transmission of viral hepatitis through hemocontact continues to be a significant public health problem because it affects numerous people at high rates throughout the world. The ongoing surveillance efforts fail to detect numerous cases of infection, which makes prevention initiatives more challenging. The study measured viral hepatitis B (HBV) and viral hepatitis C (HCV) serological marker distribution and new cases among Osh region inhabitants from 2015 through 2024. Analytical, statistic
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Written by Sarraa Dhiaa
Published on Issue 1 Vol 17, 2026
Lipophilic statins (e.g., simvastatin (SMV)) played a cytoprotective role against various injuries via mitigating neuroinflammation and attenuating oxidative damage. Doxorubicin (Dox) leads to tissue injury, particularly cardiotoxicity and brain toxicity. The present study aimed to investigate the neuroprotective potential of SMV against Dox-induced neurotoxicity in rats. A total of 56 Albino Wistar rats were housed in cages and subclassified into control male and female groups, Dox male and fem
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Written by Zalina Yuryevna Sozaeva
Published on Issue 1 Vol 17, 2026
The rising prevalence of obesity among adolescents has become a global health concern, directly contributing to the early development of cardiovascular risk. This prospective multicenter cohort study aimed to investigate the dynamics of hemodynamic mechanisms underlying the formation of arterial hypertension (AH) in this patient category during the critical period of pubertal development. The study included 498 adolescents aged 12-17 years from major cities in the North Caucasus, stratified by b
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Written by Valery Petrovich Sergun
Published on Issue 1 Vol 17, 2026
This study investigates the potential of novel biocomplexes derived from maral antlers (Pantobiol-4 formulations) to counteract cognitive impairment in a rat model of Alzheimer's disease (AD) induced by amyloid-beta 25-35 injection. Three Pantobiol preparations (Pantobiol-4-1, Pantobiol-4-2, and Pantobiol-4-3) were evaluated at different doses using behavioral (novel object recognition and passive avoidance) and biochemical [choline acetyltransferase (ChAT) activity, testosterone, and dehydr
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Written by Inas Hazem Ahmed
Published on Issue 1 Vol 17, 2026
Dracaena cinnabri is a popular medicinal plant in the peninsula of Arabia and other countries, used as an herbal cure for a variety of ailments such as astringent, analgesic, antibacterial, and antiulcer. The present research investigation sought to identify the phytochemical components and assess the hemostatic impact of Dracaena cinnabri extracts in aqueous, ethanol, and chloroform forms. Soxhlet extraction has been employed to isolate and identify secondary metabolites in plants. Several wide
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Written by Paizildaev Timur
Published on Issue 1 Vol 17, 2026
Male reproductive health is increasingly affected by environmental pollution, yet most studies focus on semen quality alone, overlooking sexual function as a relevant functional outcome. The main objective of our study is to evaluate the combined effect of the environment on men's sexual and reproductive functions by an integrated clinical-functional approach based on the International Classification of Functioning, Disability and Health (ICF). A cross-sectional study was conducted on 216 me
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Written by Yulia Sergeevna Matlahova
Published on Issue 1 Vol 17, 2026
This article presents the results of a retrospective cohort study conducted in perinatal centers of Stavropol and Vladikavkaz between 2023 and 2025. The study aimed to compare pregnancy, delivery, and neonatal outcomes during the first three months of life in women with primary toxoplasmosis based on whether they received specific therapy. The study included 110 women who received treatment, 40 women who declined therapy, and 48 non-infected pregnant women as a control group. In the treatment gr
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Written by Zalina Yuryevna Sozaeva
Published on Issue 1 Vol 17, 2026
Russia has seen a steady increase in children's participation in organized sports. Aesthetic sports, which impose strict requirements on body shape and weight, are particularly popular among young female athletes. Intensive training combined with dietary restrictions creates a risk of relative energy deficiency in sport, a condition that negatively affects the reproductive, cardiovascular, and skeletal systems. This study assessed the prevalence and patterns of health disorders in adolescent
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Written by Nifizat Seyfudinovna Kurbanova
Published on Issue 1 Vol 17, 2026
A short interpregnancy interval is a known risk factor for adverse pregnancy outcomes. However, the effectiveness of multivitamin support in women with metabolic depletion from a prior pregnancy and lactation combined with chronic prenatal stress remains poorly understood. This study examined how chronic prenatal stress, modeling a short interpregnancy interval, affects pregnancy and offspring development in rats and whether multivitamins are protective. We used 80 female Wistar rats divided int
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Written by Mansur Lechievich Muradov
Published on Issue 1 Vol 17, 2026
This study aimed to evaluate the efficacy and safety of Caucasica Adaptogen Complex in improving vitamin and mineral status in women of reproductive age living in Southern Russia and the North Caucasus. The study included a subgroup of women with limited sun exposure due to wearing covered clothing. A total of 240 female students aged 18 to 25 years from Ingush State University and Dagestan State Medical University took part in the research. Participants were divided into three equal groups: a s
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Written by Yasameen Nasih Tawfeeq
Published on Issue 1 Vol 17, 2026
This analytical cross-sectional study aimed to investigate and compare serum and salivary fructosamine and sestrin-2 levels in type 2 diabetic mellitus (T2DM) patients and controls. Methods: Ninety eight participants were enrolled in this study and subdivided into 2 subgroups, the first group (G2), which represented the control group, consisted of (49) individuals, and the forty-eight patients with DM represented the second group (G1). Serum and saliva samples collected from fasting subjects. Se
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