This study aimed to evaluate the efficacy and safety of Caucasica Adaptogen Complex in improving vitamin and mineral status in women of reproductive age living in Southern Russia and the North Caucasus. The study included a subgroup of women with limited sun exposure due to wearing covered clothing. A total of 240 female students aged 18 to 25 years from Ingush State University and Dagestan State Medical University took part in the research. Participants were divided into three equal groups: a study group (receiving the developed preparation), a comparison group (taking a standard multivitamin complex), and a control group (receiving no intervention). The preparation is a two-component system with a morning capsule containing Rhododendron adamsii and Rhaponticum carthamoides extracts combined with iron, zinc, copper, manganese, iodine, and selenium. The evening capsule contains vitamin D3, calcium, magnesium, and chamomile extract. The supplementation period lasted 60 days. Results demonstrated a statistically significant increase in the proportion of participants with normal body weight in the study group from 55.0% to 67.5%. This change resulted from a simultaneous reduction in both underweight and overweight women. Vitamin D levels normalized from 18.4 to 34.2 ng/mL, and ferritin levels increased from 22.5 to 48.3 μg/L. Asthenia scores decreased by 29%, and over 70% of participants reported increased spontaneous physical activity. This preparation may be recommended for correcting micronutrient status and normalizing body weight in women living in Southern Russia and the North Caucasus.