Written by Vitthalrao Bhimasha Khyade
Published On Issue 2 Vol 15, 2024
Enzymes are proteinaceous bio-compounds serving for catalysis and accelerating rate of bio-chemical reactions. The enzyme involved hydrolysis is dealing with disintegration of the complex compounds through utilization of enzymes (or the source of enzymes) followed by the reaction with water. The present attempt is dealing with analysis of influence of chemical protein-extraction reaction, and hydrolysis through the use of enzymes (Alcalase, Papain and Pepsin) on the functional-properties,
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Written by Mirko Marino
Published On Issue 2 Vol 15, 2024
It is necessary to find new drugs with fewer side impacts to decrease sugar in diabetics. This research aimed to investigate the impact of Capparis spinosa extract on the vital enzymes of glucose metabolism in diabetic male rats' liver cells. In the current study, a total of 60 rats were randomly divided into 6 groups. Diabetes was induced by streptozotocin intraperitoneal injection at a dose of 50 mg/kg. Insulin hormone and serum glucose were measured with the relevant kit, the activity of
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Written by S. M. Sowbaraniya
Published On Issue 2 Vol 15, 2024
A gene library is a collection of different DNA sequences from an organism, which has been cloned into vectors for ease of purification, storage, and analysis. There are two types of gene libraries based on the availability of a source of DNA used. The genomic library contains DNA fragments that represent the entire genome of an organism, whereas CDNA libraries will contain only the complementary DNA molecules synthesized from the mRNA molecules in a cell. For the construction of gene libraries,
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Written by Saida Benhmida
Published On Issue 2 Vol 15, 2024
Recently, the use of bone grafts increased in medical practice. Some bone grafts may have different mechanical and biological properties of natural bone. To improve bone grafts we need to record our knowledge about bone. In this work, we are interested in determining the chemical composition of bone fluid in the knee joint as it is a lipid-predominant fluid. Bone samples were obtained from knee cancellous bone. Samples were used of women aged 60 years old with osteoarthritis. Sample preparation
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Written by Ajay Pakalapati
Published On Issue 2 Vol 15, 2024
Monoclonal antibodies represent the rapidly expanding class of biotherapeutics having applications in the treatment of cancer, autoimmune disorders, metabolic disorders, and infectious diseases. One of the major challenges in mAb-based therapeutics development lies in the significant issue of aggregation which in turn has an impact on the quality, safety, and efficacy of the antibody drug. The presence of aggregates in the drug substance or final drug product potentially affects its biological a
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Written by C. Delgado-Montemayor
Published On Issue 2 Vol 15, 2024
One of the metabolic diseases that occurs frequently in elderly women is diabetes. In this study, the effects of diabetes on some biochemical parameters and histopathological changes in rats were investigated. In this experimental-interventional study, adult female rats were divided into four groups of 8. The first control group, the second ovariectomy group (for 55 weeks), the third induced diabetes group in the last 5 weeks of the study in mice with ovaries, and the fourth ovariectomy group (f
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Written by Ekaterina Sergeevna Kachenkova
Published On Issue 2 Vol 15, 2024
The study aimed to find out the reaction of the cardiovascular system of track and field athletes with different durations of sports experience to vestibular stimulation. The study was performed on 46 young (19.2±0.64 years old) track and field athletes. All of them were systematically trained twice or thrice a week for at least one hour a day for different lengths of time: 1 year - 15 people, 2 years - 17 people, 3 years - 14 people. The control group, also collected, consisted of 18 cli
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Written by Yulia Gennadyevna Kropova
Published On Issue 2 Vol 15, 2024
The work was carried out on five groups of pregnant sows of the Duroc breed: one control and four experimental groups of 12 animals in each group. Seven days after successful insemination and up to 4 months of gestation, sows of groups 1, 2, 3, and 4 received gamavit intramuscularly three times a week at doses of 1.0; 0.5; 0.1; and 0.05 ml/kg live weight, respectively. Animals were weighed, plasma levels of malonic dialdehyde, reduced glutathione, oxidized glutathione, triglycerides, total chole
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Written by Delia Nica-Badea
Published On Issue 2 Vol 15, 2024
This study assesses the degree of trace metal translocation from the coal matrix (lignite) into slag and ash for the following metals: Hg, Pb, Ni, and Cd. Stored in heaps in the soil and plants from the local residential environment, near the power plant. Analysis of trace metals in the multicomponent sample was carried out by AAS. Within the coal, ash, and slag samples, as well as in the vegetation and soil surrounding the power plant's sphere of impact, heavy metals were discovered. For fi
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Written by Igor Gennadievich Glamazdin
Published On Issue 2 Vol 15, 2024
Various parasitic infestations are very characteristic of wild animals. The frequency of parasites and their species composition is much richer than in farm animals. At the same time, public catering, which is an important sphere of life of modern man, under the influence of fashion and the development of gastronomic culture keeps the range of dishes offered from the meat of wild animals. Available in the sphere of public catering significant demand for products from the meat of wild animals inc
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