The work was carried out on five groups of pregnant sows of the Duroc breed: one control and four experimental groups of 12 animals in each group. Seven days after successful insemination and up to 4 months of gestation, sows of groups 1, 2, 3, and 4 received gamavit intramuscularly three times a week at doses of 1.0; 0.5; 0.1; and 0.05 ml/kg live weight, respectively. Animals were weighed, plasma levels of malonic dialdehyde, reduced glutathione, oxidized glutathione, triglycerides, total cholesterol, total protein, lipoprotein fractions, glutathione peroxidase, and superoxide dismutase activity were estimated. It was found that when administered to sows in doses of 1.0; 0.5 and 0.1 ml/kg body weight gamavit has a positive effect on morphofunctional characteristics, showing its adaptogenic and stress-protective properties, providing the optimum conditions for the course of sows gestation. Administration of the drug accelerated the growth of pregnant sows and protected their organism from stress of any origin. The results show that gamavit optimizes lipid metabolism, the activity of the antioxidant system in sows during gestation, and has a beneficial effect on the reproductive ability of animals. In the course of the performed observation, it was possible to specify the most preferable dose of gamavit for pregnant sows, capable of optimizing their biochemical and physiological parameters. This allowed us to put forward proposals for pig breeding on effective strengthening of economically beneficial traits and to increase the level of viability of pregnant sows.
