Written by Melavinka Agubechirovna Sozaeva
Published on Issue 3 Vol 16, 2025
This research article presents the results of the development and experimental evaluation of prolonged-release contact lenses for use in ophthalmology. The research aimed to create innovative delivery systems capable of overcoming the limitations of traditional eye drops, such as low bioavailability and the need for frequent use. Silicone hydrogel (Senofilcon A, Lotrafilcon B) and polymer (pHEMA) matrices modified with PLGA nanoparticles and cyclodextrins were used in the work to improve the sol
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Written by Milana Ruslanovna Gedugova
Published on Issue 3 Vol 16, 2025
The present study is devoted to the study of the features of damage to the temporomandibular joint (TMJ) in patients with rheumatoid arthritis (RA) and osteoarthritis (OA). A prospective cohort study involved 128 patients divided into three groups: 42 patients with RA, 38 with OA, and 48 healthy controls. The comprehensive examination included a clinical examination, cone beam computed tomography (CBCT), magnetic resonance imaging (MRI), electromyography of the masticatory muscles, and computer
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Written by Kuppam Chandrasekhar
Published on Issue 3 Vol 16, 2025
Microbial cell factories have emerged as sustainable platforms for producing bio-commodities such as biofuels, bioplastics, and pharmaceuticals. However, achieving industrial scalability remains hindered by challenges in strain robustness, including genetic instability, metabolic burden, and environmental stress tolerance. This review explores cutting-edge strategies in microbial engineering to enhance robustness, focusing on synthetic biology tools, adaptive laboratory evolution (ALE), and syst
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Written by Kingsley Chukwuka Amaihunwa
Published on Issue 3 Vol 16, 2025
Probiotic therapeutics represent a rapidly advancing field, with particular interest directed toward the engineering of probiotic biofilms for immune modulation and gastrointestinal (GI) health. In contrast to conventional planktonic probiotic cells, biofilm-forming strains exhibit enhanced resilience, prolonged mucosal colonization, and improved immunological interactions facilitated by their extracellular polymeric substances (EPS). These attributes confer superior therapeutic consistency and
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Written by Maneri Sujana
Published on Issue 3 Vol 16, 2025
Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), present significant global health issues, with existing treatments primarily providing limited symptom relief. Consequently, there is an increasing scientific focus on the neuroprotective capabilities of medicinal plants that have been utilized in various traditional healing practices. This review examines the therapeutic properties of Ginkgo biloba, Crocus sativus
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Written by Kuppam Chandrasekhar
Published on Issue 3 Vol 16, 2025
Microbial exopolysaccharides (EPS) are high molecular weight carbohydrate polymers secreted by bacteria, fungi, and algae, representing an important class of bio-based materials with wide ranging industrial and environmental applications. These polymers are broadly classified into capsular polysaccharides, which remain tightly bound to the microbial cell surface, and slime polysaccharides, which are released into the extracellular medium. The structural diversity of EPS, determined by variations
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