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2024 Volume 15 Issue 1

Investigating the Effectiveness of Stem Cells in Cartilage Tissue Engineering


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  1. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, P.R. China.

  2. Department of Orthopedics, The Second Hospital of Jilin University, Changchun, P.R. China.
     

  3. Department of Biobank, Division of Clinical Research, The First Hospital of Jilin University, Changchun, P.R. China.

  4. Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun, P.R. China.

  5. Department of Orthopedics, The Second Hospital of Jilin University, Changchun, P.R. China.

Abstract

Cartilage is a tissue without blood vessels and lymph, and extensive damage causes it to lose its ability to repair and regenerate. Cartilage diseases, including cartilage damage and arthritis, are increasing day by day. The damage to the cartilage causes the daily functioning of the patients to be disturbed and causes pain in the patient through wear of the bones. Common methods used to treat invasive cartilage injuries have low efficacy and include implantation of one's chondrocytes, microfracture, bone marrow stimulation, and removal of the damaged part. Common treatments are usually not definitive methods and stem cells and cartilage tissue engineering are used. The purpose of this study was to review stem cells used in cartilage cell therapy and cartilage tissue engineering. Also, in this study, cell messenger factors such as growth factors, and mechanical and environmental factors were investigated. According to the results of this study, stem cells are effective in repairing cartilage, but the mechanism and method of creating this repair have not been precisely determined. The highest security in the use of cell therapy in cartilage was related to mesenchyme cells and the most clinical use of these types of cells. Cell therapy for patients is done clinically, but cartilage tissue engineering has a long way to reach the clinical stage.


How to cite this article
Vancouver
Ding J, Le H, Zhuang X, Xu W, Wang Y, Chang F. Investigating the Effectiveness of Stem Cells in Cartilage Tissue Engineering. J Biochem Technol. 2024;15(1):1-5. https://doi.org/10.51847/cl2gvlKqdn
APA
Ding, J., Le, H., Zhuang, X., Xu, W., Wang, Y., & Chang, F. (2024). Investigating the Effectiveness of Stem Cells in Cartilage Tissue Engineering. Journal of Biochemical Technology, 15(1), 1-5. https://doi.org/10.51847/cl2gvlKqdn
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative