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2023 Volume 14 Issue 1

Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis


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Abstract

Arterial hypertension is becoming increasingly common among diseases of the cardiovascular system. The work aimed to analyze blood pressure control in patients diagnosed with arterial hypertension. Fifty physicians and 1020 patients (under 56 years of age) participated in the study. Regular use of medications was observed in 92% of the patients, and the systolic blood pressure level was 167 mm Hg. More frequent use of renin-angiotensin system blockers compared with diuretics and calcium antagonists was noted, both in monotherapy and in combination therapy. Target BP was achieved in 66% of cases within three months by therapy with amlodipine and retarded indapamide. The majority of patients adhered to the prescribed therapy (97%). The effectiveness of amlodipine and indapamide therapy was in direct correlation with baseline BP values. Significant factors were smoking (lower efficacy), and gender (higher in women). The degree of BP reduction following combined therapy with amlodipine and indapamide was determined to be directly correlated with the beginning BP level. At the same time, female patients and non-smokers see more pronounced dynamics of BP lowering. Pre-treatment is also a crucial element; statins and renin system blockers greatly lower blood pressure when used together.


How to cite this article
Vancouver
Korylchuk N, Riabushko R, Haman I, Krasnova A, Dovzhuk N. Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis. J Biochem Technol. 2023;14(1):64-9. https://doi.org/10.51847/UHBo9d7ziP
APA
Korylchuk, N., Riabushko, R., Haman, I., Krasnova, A., & Dovzhuk, N. (2023). Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis. Journal of Biochemical Technology, 14(1), 64-69. https://doi.org/10.51847/UHBo9d7ziP
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative