TY  - JOUR
T1  - Arterial Hypertension in Ukraine: Medical and Social Problems of Pathogenesis
A1  - Neonila Korylchuk
A1  - Roman Riabushko
A1  - Iryna Haman
A1  - Anatolija Krasnova
A1  - Natela Dovzhuk
JF  - Journal of Biochemical Technology
JO  - J Biochem Technol
SN  - 0974-2328
Y1  - 2023
VL  - 14
IS  - 1
DO  - 10.51847/UHBo9d7ziP
SP  - 64
EP  - 69
N2  - Arterial hypertension is becoming increasingly common among diseases of the cardiovascular system. The work aimed to analyze blood pressure control in patients diagnosed with arterial hypertension. Fifty physicians and 1020 patients (under 56 years of age) participated in the study. Regular use of medications was observed in 92% of the patients, and the systolic blood pressure level was 167 mm Hg. More frequent use of renin-angiotensin system blockers compared with diuretics and calcium antagonists was noted, both in monotherapy and in combination therapy. Target BP was achieved in 66% of cases within three months by therapy with amlodipine and retarded indapamide. The majority of patients adhered to the prescribed therapy (97%). The effectiveness of amlodipine and indapamide therapy was in direct correlation with baseline BP values. Significant factors were smoking (lower efficacy), and gender (higher in women). The degree of BP reduction following combined therapy with amlodipine and indapamide was determined to be directly correlated with the beginning BP level. At the same time, female patients and non-smokers see more pronounced dynamics of BP lowering. Pre-treatment is also a crucial element; statins and renin system blockers greatly lower blood pressure when used together.
UR  - https://jbiochemtech.com/article/arterial-hypertension-in-ukraine-medical-and-social-problems-of-pathogenesis-tl81e1p01qcpewq
ER  -