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2020 Volume 11 Issue 4

Study of the Features of Choledocholithiasis in Elderly Patients


Almohamad Almahmud Tamim, Alexey Klimov
Abstract

Introduction: Choledocholithiasis occurs most commonly, the probability of calculi in the bile duct increases significantly with the age of patients. Our study aimed to assess the situation of choledocholithiasis in Moscow, and study the characteristics of the disease in elderly patients. Methods: This was a retrospective study, including patients referred to the surgical department of the V. V. Vinogradov state medical center in Moscow, for the periods between 2017 - 2019. Data were collected from the records of the patients and cross-checked with endoscopic and cholangiography images. A total of 140 patients were included in this study. Results: The mean age of the patients was 79.9 years. Patients presented with obstructive jaundice (58.57%), cholangitis (25%), biliary colic or upper abdominal pain (14.22%), and acute biliary pancreatitis (2.14%). There were 15 (10.71%) post-cholecystectomy patients. Concomitant gallbladder stones were found in 95 patients (67.85%). Juxta-papillary diverticula were found in 19 patients (13.57%). Seven patients (5%) and 15 patients (10.71%) were found to have common bile duct strictures and choledochal cysts, respectively. Stones were commonly found in the distal common bile duct (68.57%). A majority of the patients had a single stone (47.85%). In 115 patients (82.14%), the size of the largest stones measured between 0.5-1.5 cm. Conclusion: Choledocholithiasis affects the elderly ages of most patients, the percentage of its occurrence has increased in females compared to that of males. The most common symptoms of the disease were obstructive jaundice, with the formation of distal stones, with no primary formation being. These characteristics were favorable for successful endoscopic removal of stones.


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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

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AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative