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2023 Volume 14 Issue 1

Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical


Valerii Panteleevich Kartashev, Sun Xingyuan, Ilya Nikolaevich Medvedev, Elena Sergeevna Tkacheva, Nadezhda Viktorovna Vorobyeva
Abstract

All aging rats included in the study had standard signs of aging. As a result of regular physical activity during 60 days of observation, the existing manifestations of aging weakened in these rats. Initially, in aging rats, the processes of lipid peroxidation in erythrocytes were enhanced due to a decrease in the activity of erythrocyte antioxidant protection. Against the background of increased physical activity in the structures of erythrocytes of aging rats, the amount of lipid peroxidation products gradually decreased and after 60 days of observation approached control level 2. In aging rats, an initially low content of erythrocyte-discocytes in the blood was found. At the same time, their blood contained an excess content of reversibly and irreversibly altered erythrocytes. As a result of regular physical activity, these indicators gradually approached the control level of 2. Initially, aging rats had a high amount of erythrocytes in the aggregates and a large number of erythrocyte aggregates with a low number of isolated erythrocytes. By the end of the experiment, these indicators in the experimental group approached levels close to control 2. Systematic feasible muscle loads were able to lead aging rats to the weakening of the existing microrheological disorders of their erythrocytes.


How to cite this article
Vancouver
Kartashev VP, Xingyuan S, Medvedev IN, Tkacheva ES, Vorobyeva NV. Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical. J Biochem Technol. 2023;14(1):50-6. https://doi.org/10.51847/GGLSMMHC5s
APA
Kartashev, V. P., Xingyuan, S., Medvedev, I. N., Tkacheva, E. S., & Vorobyeva, N. V. (2023). Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical. Journal of Biochemical Technology, 14(1), 50-56. https://doi.org/10.51847/GGLSMMHC5s
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative