%0 Journal Article
%T Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical
%A Valerii Panteleevich Kartashev
%A Sun Xingyuan
%A Ilya Nikolaevich Medvedev
%A Elena Sergeevna Tkacheva
%A Nadezhda Viktorovna Vorobyeva
%J Journal of Biochemical Technology
%@ 0974-2328
%D 2023
%V 14
%N 1
%R 10.51847/GGLSMMHC5s
%P 50-56
%X All aging rats included in the study had standard signs of aging. As a result of regular physical activity during 60 days of observation, the existing manifestations of aging weakened in these rats. Initially, in aging rats, the processes of lipid peroxidation in erythrocytes were enhanced due to a decrease in the activity of erythrocyte antioxidant protection. Against the background of increased physical activity in the structures of erythrocytes of aging rats, the amount of lipid peroxidation products gradually decreased and after 60 days of observation approached control level 2. In aging rats, an initially low content of erythrocyte-discocytes in the blood was found. At the same time, their blood contained an excess content of reversibly and irreversibly altered erythrocytes. As a result of regular physical activity, these indicators gradually approached the control level of 2. Initially, aging rats had a high amount of erythrocytes in the aggregates and a large number of erythrocyte aggregates with a low number of isolated erythrocytes. By the end of the experiment, these indicators in the experimental group approached levels close to control 2. Systematic feasible muscle loads were able to lead aging rats to the weakening of the existing microrheological disorders of their erythrocytes.
%U https://jbiochemtech.com/article/physiological-changes-in-the-erythrocytes-of-an-aging-organism-experiencing-physical-ohritahqqi9lhlf