Basil (Ocimum basilicum L) is a plant that belongs to the Lamiaceae family and is known for its pharmacological and therapeutic properties, as it is rich in active biological substances, which endow it with antioxidant and anti-inflammatory activities. Many people from all over the world use basil in traditional medicine, including North African countries, especially Algeria, which they use to treat many organic and infectious diseases. On the other hand, according to scientific reports, the O. basilicum plant contains most of the major and biologically active molecules such as flavonoids, phenols, tannins, steroids, glycosides, and reduced sugars. Pharmacological studies also indicate that the plant has antioxidant, anti-inflammatory, analgesic and antibacterial activities. In silico tools, a compound's ability to block a receptor can be successfully studied by combining many in silico approaches. There have been reports of natural chemicals of O. basilicum having anticancer action. In conclusion, O. basilicum may be one of the best sources of plant medicines that can be used to treat many acute and chronic diseases.