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2022 Volume 13 Issue 4

Collagen Hydrolysates in the Prevention and Treatment of Arthritis


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Abstract

The present review examines the role of collagen hydrolysates in the treatment and prevention of joint diseases. Collagen is the main structural protein of bones, cartilage, ligaments, and tendons in joints. Hydrolyzed collagen, as a source of specific amino acids, can be a building material for the formation of collagen fibrils in connective tissues. Enzymatic hydrolysis of chicken cartilage made it possible to obtain a complex of collagen type II hydrolysate and glycosaminoglycans. In clinical studies, hydrolysates of cutaneous collagen, type II cartilaginous collagen, and type II non-denatured cartilaginous collagen were tested. The use of collagen hydrolysates for a long time (5-6 months) allowed for improving the functioning of the knee joint in patients not only with mild but also with severe osteoarthritis. Nutraceuticals from type II collagen hydrolysates in combination with vitamin C more effectively affect the formation of collagen fibrils, and proteoglycans in the cartilage matrix and thus can affect the increase in joint mobility. Nutriciology, as a branch of modern biopharmaceutics, represents its new direction and explores possible mechanisms and ways to prevent human diseases.


How to cite this article
Vancouver
Kryuchkova AV, Tunguzbieva RU, Tokaeva KS, Isaev AA, Elmaeva LR, Mikhailenko VV. Collagen Hydrolysates in the Prevention and Treatment of Arthritis. J Biochem Technol. 2022;13(4):54-9. https://doi.org/10.51847/3SWKk0nMnP
APA
Kryuchkova, A. V., Tunguzbieva, R. U., Tokaeva, K. S., Isaev, A. A., Elmaeva, L. R., & Mikhailenko, V. V. (2022). Collagen Hydrolysates in the Prevention and Treatment of Arthritis. Journal of Biochemical Technology, 13(4), 54-59. https://doi.org/10.51847/3SWKk0nMnP
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative