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2023 Volume 14 Issue 1

Application of Raman Spectroscopy to Study the Mineralization of Bone Regenerates


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Abstract

Assessment of the state of bone tissue during biopsy examination of the material of patients with degenerative or traumatic diseases is a very urgent task of modern medicine. Such an assessment makes it possible to characterize the regenerative processes at the site of the bone defect and to choose the most effective treatment strategies. Currently, in the study of bone tissue, methods of X-ray examination and survey histological staining are used. Such methods do not allow a highly sensitive analysis of individual components of the cellular substance. One approach to solving this problem can be the use of Raman spectroscopy. In contrast to infrared spectroscopy, Raman spectroscopy records in the optical range, which ensures high sensitivity and ease of use. Raman spectroscopy is a non-contact, non-destructive testing method suitable for working with substances in any phase. In this scientific work, a study of the distribution of hydroxyapatite in a section of the regenerative material of the parietal bone of the rat skull is carried out. As a result, it was shown that the Raman spectroscopy method can be used to determine the characteristics of the formation, mineralization, and maturation of bone tissue, to identify loci with maximum and minimum mineralization.


How to cite this article
Vancouver
Tedeeva AV, Sataev AR, Batraeva ST, Gabitaeva TN, Magomedsaugitova NN, Azatyan AA. Application of Raman Spectroscopy to Study the Mineralization of Bone Regenerates. J Biochem Technol. 2023;14(1):22-6. https://doi.org/10.51847/nVm55ojLS7
APA
Tedeeva, A. V., Sataev, A. R., Batraeva, S. T., Gabitaeva, T. N., Magomedsaugitova, N. N., & Azatyan, A. A. (2023). Application of Raman Spectroscopy to Study the Mineralization of Bone Regenerates. Journal of Biochemical Technology, 14(1), 22-26. https://doi.org/10.51847/nVm55ojLS7
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative