TY  - JOUR
T1  - Application of Raman Spectroscopy to Study the Mineralization of Bone Regenerates
A1  - Anzhela Valerievna Tedeeva
A1  - Ahmed Ruslanovich Sataev
A1  - Saudi Timurlanovna Batraeva
A1  - Tamara Nugzarievna Gabitaeva
A1  - Napisat Nutsalovna Magomedsaugitova
A1  - Ani Arkadievna Azatyan
JF  - Journal of Biochemical Technology
JO  - J Biochem Technol
SN  - 0974-2328
Y1  - 2023
VL  - 14
IS  - 1
DO  - 10.51847/nVm55ojLS7
SP  - 22
EP  - 26
N2  - Assessment of the state of bone tissue during biopsy examination of the material of patients with degenerative or traumatic diseases is a very urgent task of modern medicine. Such an assessment makes it possible to characterize the regenerative processes at the site of the bone defect and to choose the most effective treatment strategies. Currently, in the study of bone tissue, methods of X-ray examination and survey histological staining are used. Such methods do not allow a highly sensitive analysis of individual components of the cellular substance. One approach to solving this problem can be the use of Raman spectroscopy. In contrast to infrared spectroscopy, Raman spectroscopy records in the optical range, which ensures high sensitivity and ease of use. Raman spectroscopy is a non-contact, non-destructive testing method suitable for working with substances in any phase. In this scientific work, a study of the distribution of hydroxyapatite in a section of the regenerative material of the parietal bone of the rat skull is carried out. As a result, it was shown that the Raman spectroscopy method can be used to determine the characteristics of the formation, mineralization, and maturation of bone tissue, to identify loci with maximum and minimum mineralization.
UR  - https://jbiochemtech.com/article/application-of-raman-spectroscopy-to-study-the-mineralization-of-bone-regenerates-2gfplgxngajalvn
ER  -