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2020 Volume 11 Issue 3

The Impact of Serum Ferritin on Exfoliated Cells Morphology from Buccal Mucosa among Iron Deficiency Anemia Patients: Morphometric Study


Osman Mohammed Elmahi, Nusaiba Mohammed Alsammani, Yousif Mohammed Elmosaad, Lienda Bashier Eltayeb, Hisham Ali Waggiallah
Abstract

Iron deficiency anemia is the world's most common dietary deficiency-affecting people of all ages and economic classes. The current research was performed to assess the quantitative changes in the cytoplasmic diameter CD, nuclear diameter ND, and nuclear to cytoplasmic ratio (N/C) of squamous cells collected from iron deficiency anemia patients' buccal smears and also to evaluate the effects of serum ferritin concentrations on cellular morphometry. This was a prospective cross-sectional study. The research group consisted of twenty-five cases of iron deficiency and twenty-five cases of apparently healthy controls. Scrapings were taken from both group's buccal mucosa and stained with Papanicolaou stain. The ratio ND, CD, and N/C were measured using the Optika camera microscope. The results of this study revealed a highly significant and positive correlation between serum ferritin and ND, and a significant inverse correlation with ND and N/C ratio, as well as significant differences in anemic patients and controls in CD, ND, and N/C ratio. The significant reduction in serum ferritin from anemia with iron deficiency contributes to morphometric changes in exfoliated buccal mucosal cells.


How to cite this article
Elmahi O M, Alsammani N M, Elmosaad Y M, Eltayeb L B, Waggiallah H A. The Impact of Serum Ferritin on Exfoliated Cells Morphology from Buccal Mucosa among Iron Deficiency Anemia Patients: Morphometric Study. J Biochem Technol 2020;11(3):21-7
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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative