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2020 Volume 11 Issue 2

Synergistic effect of Zinc Oxide Nanoparticles and Guava Leaf extract for Enhanced antimicrobial activity against Enterotoxigenic Escherichia coli


Anurag Jyoti, Mohit Agarwal, Rajesh Singh Tomar
Abstract

Safe drinking water in an urban city has been a great challenge for the human population. Consumption of contaminated water may lead to the occurrence of several diseases. Enterotoxigenic Escherichia coli (ETEC) is an enteric pathogen that can survive even in treated drinking water and cause watery diarrhea. The pathogen harbors virulent and drug-resistant genes responsible for its virulence and antibiotic resistance. Persistence of such strains of ETEC is often associated with disease outbreaks. The present work involves the drug-resistance pattern of ETEC, isolated from drinking water. Zinc Oxide nanoparticles were synthesized using a chemical method and their antimicrobial effects were assessed against drug-resistant strains. In order to increase the antimicrobial efficacy of nanoparticles, guava leaf extracts were used and their synergistic study with Zinc Oxide nanoparticles was carried out. Results showed the prevalence of drug-resistant ETEC in the drinking water of Gwalior city. Our study further indicates the potential antimicrobial activity of Zinc Oxide nanoparticles in synergy with guava leaf extract against ETEC.


How to cite this article
Jyoti A, Agarwal M, Tomar R S. Synergistic effect of Zinc Oxide Nanoparticles and Guava Leaf extract for Enhanced antimicrobial activity against Enterotoxigenic Escherichia coli. J Biochem Technol 2020;11(2):17-23
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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative