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2020 Volume 11 Issue 2

Surgical Treatment of Patients with Severe Acute Pancreatitis


Samara M., Klimov A.E., Persov M.Yu., Kirtadze D.G., Barkhudarov A.A.
Abstract

The aim is to study the clinical profiles of patients with severe AP treated surgically during their stay in the hospital. Methods and materials: a result analysis of treating 125 patients with severe forms of acute pancreatitis was carried out. All patients in the preoperative period were imaged through ultrasound scanning (hereinafter referred to as the US). 40 patients were also imaged through computed tomography (hereinafter referred to as CT). US and CT data obtained before surgery were compared with intraoperative ones. Results: All patients were operated on. Operation indications involved: peritonitis clinical picture in 117 patients (93.6%), arosive vessel bleeding in the necrotizing and sequestrum area in 4 patients (3.2%), jaundice growth in 4 patients (3.2%). 80 patients showed infected pancreonecrosis, 80 patients showed retroperitoneal tissue disease. 34 patients died. Factors affecting the disease outcome were revealed: infected pancreonecrosis, retroperitoneal tissue disease, cachexia, obesity, alcoholism, coronary heart disease, arterial hypertension and hepatic disorders, total ASSES scores are higher than 13 upon admission and before surgery, as well as higher than 16 on the 1st-2nd and 3rd-4th day after the operation. Conclusion: The complex use of computed tomography and ultrasound when diagnosing severe forms of acute pancreatitis increases the informational value of these methods to almost 100%.


How to cite this article
Samara M, Klimov A E, Persov M Y, Kirtadze D G, Barkhudarov A A. Surgical Treatment of Patients with Severe Acute Pancreatitis. J Biochem Technol 2020;11(2):60-4
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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative