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2020 Volume 11 Issue 1

Overweight and Obesity and the Immune System, Lipids and C-reactive Protein in Young and Middle-aged Saudi Female University Workers


Sawsan Hassan Mahassni
Abstract

Saudi Arabia is one of the Middle Eastern countries with the highest prevalence of overweight and obesity in adults and especially in females. Overweight and obesity affect many systems in the body leading to increased mortality, morbidity, and risk for many diseases. This study aimed to determine the effects of overweight and obesity on the immune system cells, hematology, lipid profile, and C-reactive protein (CRP) concentration in 62 randomly chosen Saudi female university employees with an age range of 24-52 years. Blood samples were collected from the subjects and they were categorized using the body mass index (BMI), Waist-to-hip ratio (WHR), and waist circumference (WC) as adiposity measures. All results were compared to the controls. The lymphocyte count for the obese BMI group and eosinophil percent for the overweight BMI group were significantly higher. The total leucocyte and neutrophil counts, and triglyceride concentration were significantly higher for the WHR high-risk group. The total leucocyte, neutrophil, red blood cell counts, and concentrations of CRP and triglyceride were significantly higher for the WC high risk; the neutrophil percent was significantly lower for the WC moderate-risk group, and the basophil percent was significantly lower for the WC high-risk group. The remaining parameters and comparisons were not significantly different between the groups of each adiposity measure. In conclusion, overweight and obesity lead to some effects on the immune system and higher inflammation as evidenced by the higher total and some types of leucocytes and CRP concentrations. The effects on hematology and lipids were minimal. Finally, the WC is the best measure of adiposity for the subjects of the study since it resulted in more significant differences between groups compared to the BMI and WHR.


How to cite this article
Mahassni S H. Overweight and Obesity and the Immune System, Lipids and C-reactive Protein in Young and Middle-aged Saudi Female University Workers. J Biochem Technol 2020;11(1):49-56
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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative