Evaluation of Interleukin IL-1β, TNF-α, and VDB Protein Levels in Serum of Patients with Chronic Periodontitis

Sara A. Hatem , Zaizafon N. Nsaif , Eaman A. S. AL-Rubaee

Abstract

Aim: The aim of the study was to evaluate the levels of Interleukin IL-1β, TNFα, and VDB Protein in the serum of patients with chronic periodontitis. Materials and methods: Serum samples of 60 persons, aged 25-55 years with chronic periodontitis were collected as patients group; samples of serum were obtained from 30 healthy subjects aged 25-55 years as the control group. Interleukin IL-1β, TNF-α, and VDB protein levels were measured by enzyme-linked immune sorbent assay (ELISA) kit. Results: The levels of Interleukin IL-1β, TNF-α, and VDB protein in serum showed a significant increase in the patient group than the healthy group. On the other hand, VDB protein was not significantly correlated with IL-1β and TNF-α in patients.


How to cite:
Hatem S A, Nsaif Z N, AL-Rubaee E A S. Evaluation of Interleukin IL-1β, TNF-α, and VDB Protein Levels in Serum of Patients with Chronic Periodontitis. J Biochem Technol 2020;11(1):14-7

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