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2020 Volume 11 Issue 3

A Study on the Synthesis, Antimicrobial Activity, and Rapd Analysis of 3-phenyl-1,5-bis(4-(trifluoromethyl)phenyl)-1H-pyrazole


Adnan Cetin, Sedat Bozari
Abstract

3-phenyl-1,5-bis(4-(trifluoromethyl)phenyl)-1H-pyrazole was synthesized and its structure was characterized by IR, NMR, and Elemental Analysis. The antimicrobial effects of pyrazole were investigated against seven bacteria (Bacillus subtilis ATCC 6633, Staphylococcus aureus 6538, Bacillus megaterium DSM 32 as gram-positive bacteria and Enterobacter aerogenes ATCC 13048, Pseudomonas aeruginosa 9027, Klebsiella pneumoniae RSKK 574 and Escherichia coli ATCC 25922) and three fungi organisms (Candida albicans ATCC 10231, Yarrovia lipolytica and Saccharomyces cerevisiae). Furthermore, the genomic stability values of designed pyrazole were observed in Hordeum vulgare and Amaranthus retroflexus L. from seeds based on random amplified-polymorphic DNA (RAPD) patterns compared to the five primers.


How to cite this article
Cetin A & Bozari S. A Study on the Synthesis, Antimicrobial Activity, and Rapd Analysis of 3-phenyl-1,5-bis(4-(trifluoromethyl)phenyl)-1H-pyrazole. J Biochem Technol 2020;11(3):77-83
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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative