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2012 Volume 4 Issue 1

A Review on production of echinocandins by Aspergillus sp


Abstract
For the last two decades Echinocandins have successfully emerged out & gained considerable importance when introduced in the World  Pharma Market. Echinocandins are  new novel class of drugs  for fungal infections. Echinocandins inhibit an enzyme necessary for the formation of fungal cell wall components, thus  disrupts the integrity of the cell wall and eventually leads to cell death. They are fungicidal and less toxic to the host by virtue of their novel mechanism of action. Aspergillus sp is the most investigated species among many fungal species producing secondary metabolites of this kind. Bioprocess parameters help us to understand the relationship between the fungal growth and its secondary metabolite (Echinocandins) in large scale The objective  of the present review is to provide an updated & thoughtful overview for the appropriate fermentative production methodology.

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J BIOCHEM TECH
J BIOCHEM TECH
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative