The immune response is the body's capability to keep itself safe by providing defense against potentially dangerous substances. It includes specific responses to most microbes in addition to specialized and greatly precise responses to a specific offender. Positive immunological and histological alterations in hepatically damaged rats, brought about by Artemisia judaica. An animal that was confined to a cage for the experiment. The rats were kept in groups of six and fed a diet that served as a baseline for 7 days before the experiment was conducted. The first group of rats (C-ve) were fed only their usual food for 28 days as a control. To kill off the remaining rats (n=24), carbon tetrachloride (Ccl4) was injected into their veins. Four groups were given experimental diets containing varied amounts (5, 10, or 15 percent Artemisia judaica) and one group was given a diagnosis of the condition but no experimental diet. Findings indicated that 15 percent Artemisia judaica resulted in the greatest white blood cell counts in treated groups, whereas 10% of Artemisia judaica resulted in the lowest value. The findings also showed when contrasted with (C +ve), Artemisia judaica doses of 5 percent and 15 percent provide the greatest significant increases in the lymphocytic transformation index. The study recommended feeding Artemisia judaica to enhance immunity and improve the histology of the liver.