It is necessary to develop and implement wide zootechnical practice techniques and methods that allow more fully realizing the genetic potential of meat productivity of fattening young animals. In this paper, the authors study the features of nitrogen exchange and calcium and phosphorus balance in steers of the Simmental breed and its first-generation crossbreds with red steppe and black-motley cattle. The impact of steer genotype on the efficiency of fodder nitrogen use on protein synthesis in muscular tissue was noted. The coefficient of utilization of nitrogen from consumed fodder in bulls of group I was 17.70% and from digested ― 26.23%, in group II ― 16.79% and 25.35%, and in group III ― 18.06% and 26.32%, respectively. Similar intergroup differences were established for calcium and phosphorus balance. The calcium utilization rate of groups I, II, and III was 42.16%, 40.79%, and 42.39%, and the phosphorus utilization rate was 40.63%, 40.06%, and 41.18%, respectively.