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2023 Volume 14 Issue 2

The Effect of Regular Physical Activity on Platelet Activity in Men of Mature Age


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Abstract

At present, much attention is paid to various aspects concerning the impact of systematic muscular load on platelet parameters. In our study, we examined 107 healthy mature males. They were divided into 4 groups. In this study, we determined the mean platelet volume, their aggregation activity when introduced into plasma with 2.5, 5, and 10 μM ADP, and the amount of GP IIb-IIIa and GP Ib on the platelet surfaces. With an increase in daily muscle activity, the examined patients showed a weakening in the process of platelet aggregation in relation to all the applied concentrations of ADP, the content of adenosine phosphates in them, and the secretion of adenosine phosphates from them, the platelet level of actin and myosin, a decrease in platelets size and a reduction in the GP IIb-IIIa and GP Ib expressiveness. There was revealed the correlation between the volume of platelets, on the one hand, and platelet aggregation, the adenosine phosphates content in them and secretion from them, the level of actin and myosin self-assembly, and the density of GP IIb-IIIa and GP Ib receptors on platelet membranes, on the other hand, which, to a greater extent, manifested itself in the most physically active people. The changes in platelet parameters that occur in males of the second mature age if the distance traveled per day increases indicate the possibility of their optimization through a rational and controlled increase in physical activity within a day.


How to cite this article
Vancouver
Medvedev IN, Komarov MN, Karpov VY, Dorontsev AV, Dorontseva XA, Sysoeva E. The Effect of Regular Physical Activity on Platelet Activity in Men of Mature Age. J Biochem Technol. 2023;14(2):50-60. https://doi.org/10.51847/59bnth85LH
APA
Medvedev, I. N., Komarov, M. N., Karpov, V. Y., Dorontsev, A. V., Dorontseva, X. A., & Sysoeva, E. (2023). The Effect of Regular Physical Activity on Platelet Activity in Men of Mature Age. Journal of Biochemical Technology, 14(2), 50-60. https://doi.org/10.51847/59bnth85LH
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

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AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

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FOCUS AND SCOPE
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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative