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2019 Volume 10 Issue 1

The Biochemical Effects of Lead Concentration on Oxidative Stress Parameters in Workers


Hamzeh Salehzadeh, Mehrzad Ebrahemzadih, Mohammad Reza Nourani, Fatemeh Mohebbinia and Ramezan Ali Taheri
Abstract

The goal of this study was to determine the blood lead concentration in various occupational workers in Sanandaj and its effects on oxidative stress parameters and other blood parameters. This descriptive-analytic study was carried out in Sanandaj, Iran. A total of 278 subjects were selected as the sample size for this study, of which 64 did not have exposure to theoccupational lead, and 214 had the occupational exposure tolead. The blood lead levels were measured by the atomic absorption spectrophotometer apparatus AA6800. Oxidative stress parameters and other blood parameters were measured by special devices. There was a significant positive relationship between the blood lead concentration and the oxidative stress parameters including lipid peroxidation, malondialdehyde, glutathione, antioxidant serum, and catalase. There was a significant negative relationship between the blood lead concentration and hematological parameters. Also, there was a significant positive relationship between the blood lead level and the lead concentration in the air.


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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative