Toxic and heavy metals are non-biodegradation pollutants in the environment that can affect human health. The levels of these metals can be analyzed with some biological materials, and they may be used to monitor changes in the human body. The levels of selected toxic and heavy metals (Hg, Pb, Ni, Se, Mn, As, Cr, Cd, and Zn) in the scalp hair of male smokers and non-smokers were determined to investigate dietary exposure to various chemical metals pollutants in Saudi Arabia Population. All investigated samples were collected from cigarette smokers, hookah smokers, and non-smoker (control) volunteers in Hail city. The samples were digested using microwave acid digestion, after which the analysis was carried out by inductively coupled plasma mass spectrometry (ICPMS). The data obtained from control samples were used for purpose of comparison and the smoking state of the family was considered. A systematic analysis investigation was carried out for all samples taking into consideration the number of smoked cigarettes and/ or hookah per day as well as the smoking duration. Finally, the obtained results showed the presence of a statistically significant relationship between smoking and the heavy metal concentration detected in smoking samples, which may play a very important guide for many respective antismoking organizations.
