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2012 Volume 3 Issue 4

Role of chromosome 3p22.3 in the development of uterine cervical cancer


Abstract
AbstractThe aim of this study was to examine the expression of chromosome 3p22.3 and its role in the development of uterine cervical cancer. The 42 unrelated individuals freshly operated specimens from the cervical region with their corresponding normal or peripheral blood leucocytes (PBL) were collected from the patients. The specimens were undertaken for microdissection procedure. The detection of human papilloma virus (HPV) was done by PCR using the primers MY09 and MY11. The 3p22.3 region appeared to be associated with the development of cervical carcinoma because of significant increase of loss of heterozygosity frequency. The differential deletions in the chromosome 3p22.3 region show that this region plays an important role in the development of the uterine cervical cancer.

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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative