The study aimed to look into the prevalence of community-acquired methicillin-resistant Staphylococcus aureus in the nasal carriage of Delta State University students. 100 nasal swabs (samples) were collected from the anterior nares of both male and female students of DELSU and were cultured on Mannitol salt Agar. Staphylococcus aureus species were isolated. A standard biochemical identification test was carried out to identify the organism. An antibiotic susceptibility test was carried out for Staphylococcus aureus using the Agar well diffusion method and the zone of inhibition was determined. The average readings were taken of the zone of inhibition and were compared with the Kirby Bauer Standard for Staphylococcus aureus. zones of inhibitions within the range (≤10) were used to determine the Methicillin-resistant Staphylococcus aureus (MRSA). Out of the 100 samples collected and cultured, 93 were Staph species 33(35.5%) were found to be Staphylococcus aureus while the remaining 60(64.5%) were other species of Staphylococcus aureus. Only the Staphaureus species was worked on and out of the 33(35.5%) Staphylococcus aureus, 23(69.7%) of the Staphylococcus aureus were found to be methicillin-resistant. In comparison, 10(30.3%) were found to be sensitive to Oxacillin disk which was used as a reference to methicillin antibiotics because it's closely related to methicillin. This study shows increased Staphylococcus aureus methicillin resistance, therefore suggesting the prevalence of CA-MRSA in the nasal cavity of DELSU Students and suggesting that more work has to be done and awareness campaigns on how to curtail the spread of methicillin-resistant Staphylococcus aureus.
