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2021 Volume 12 Issue 4

Phytochemical, Free Radical Scavenging and Antimicrobial Activities of Glycyrrhiza glabra L. rhizomes Collected from Algeria


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Abstract

In the world of the pharmaceutical industry, plants are considered a major source of medicines due to the presence of bioactive compounds, which provide many physiological effects on the human body. Given the toxicity and unwanted side effects of synthetic molecules, there is an increasing demand for natural drugs. In this context, the present study focused on the phytochemical and biological study of extracts of the medicinal plant Glycyrrhiza glabra L.

The results of the phytochemical screening revealed the analyst plant contains active Chemical Compounds, except for the Imodals. Compounds also the extraction of phenolic using organic polarized solvents showed that the highest yield was with methanol extract (9, 2%) compared to the rest of the extracts. The quantitative estimate of these extracts showed that the methanol extract contains the largest quantity of phenols and flavonoids (50,37±2,14 mg AGE / g Ext) and (8,1±1,2 mg QE / g Ex) respectively. The biological study through the DPPH test showed that the extracts of the rhizomes of the plant G. glabra possess antioxidant capacity, as the methanol extract showed a high inhibition capacity estimated at (IC50= 35±0.59 µg/ml). As for the anti-bacterial activity, it showed significant activity of G.glabra plant extracts against the tested bacterial strains, where the largest inhibition zone diameter was 19 mm with the methanol Extract against Bacillus cereus (ATCC 11778).


How to cite this article
Vancouver
Benbott A, Karouche S, Mosbah C, Boukeria S, Yahia A. Phytochemical, Free Radical Scavenging and Antimicrobial Activities of Glycyrrhiza glabra L. rhizomes Collected from Algeria. J Biochem Technol. 2021;12(4):78-83. https://doi.org/10.51847/0ShxsdgtLC
APA
Benbott, A., Karouche, S., Mosbah, C., Boukeria, S., & Yahia, A. (2021). Phytochemical, Free Radical Scavenging and Antimicrobial Activities of Glycyrrhiza glabra L. rhizomes Collected from Algeria. Journal of Biochemical Technology, 12(4), 78-83. https://doi.org/10.51847/0ShxsdgtLC
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative