In the world of the pharmaceutical industry, plants are considered a major source of medicines due to the presence of bioactive compounds, which provide many physiological effects on the human body. Given the toxicity and unwanted side effects of synthetic molecules, there is an increasing demand for natural drugs. In this context, the present study focused on the phytochemical and biological study of extracts of the medicinal plant Glycyrrhiza glabra L.
The results of the phytochemical screening revealed the analyst plant contains active Chemical Compounds, except for the Imodals. Compounds also the extraction of phenolic using organic polarized solvents showed that the highest yield was with methanol extract (9, 2%) compared to the rest of the extracts. The quantitative estimate of these extracts showed that the methanol extract contains the largest quantity of phenols and flavonoids (50,37±2,14 mg AGE / g Ext) and (8,1±1,2 mg QE / g Ex) respectively. The biological study through the DPPH test showed that the extracts of the rhizomes of the plant G. glabra possess antioxidant capacity, as the methanol extract showed a high inhibition capacity estimated at (IC50= 35±0.59 µg/ml). As for the anti-bacterial activity, it showed significant activity of G.glabra plant extracts against the tested bacterial strains, where the largest inhibition zone diameter was 19 mm with the methanol Extract against Bacillus cereus (ATCC 11778).
