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2011 Volume 3 Issue 2

Parametric constraints on the dynamic behavior of immobilized enzyme kinetics in a microreactor


Abstract
The observed kinetics of reactions catalyzed by immobilized enzymes in microreactors may differ from their kinetics in well-mixed solution-phase reactors. While the steady-state differences have been analyzed before, the time-dependent differences have not been explored. In the present study, therefore, an initial feasibility analysis has been conducted to identify permissible regions for the kinetic parameters for dynamics solutions to exist. For a reaction catalyzed by alkaline phosphatase, it has been shown that the choices of the values of three vital parameters are inter-related and restricted to certain nonlinear loci. These limits add to the limits imposed by thermodynamic requirements, and they are important in determining dynamic behavior.  

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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative