Background: As nutrition is an integral part of human material life, it is inseparable from his spiritual life as well. Objectives: This study aimed to assess interrelationship between spiritual health and nutrition in Islam. Method: The research method is mainly desk research (religious texts, the way of Islamic scholar) and PubMed. Results: Islam as a religion is linked to nutrition recommendation. Food consumption and meal time Islamic orders are not only proper for physical health but also for other aspects especially for spiritual wellbeing. It can be concluded that one's aim of food consumption should be obedience to God and spiritual perfection. For Muslim, foods should be hygienic, healthy and prepared in halal way. Moderation in food consumption recommended in religious narration and excessive eating and drinking not only harmful for physical health but also is opposed to spirituality. Of course, the nature of some foods is more appropriate with spirituality mentioned in this article. Conclusion: The result is that the guidance of the holy Quran and traditions can make a major contribution to human society in solving physical and emotional difficulties caused by malnutrition (defined by religion) facing humanity today.