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2021 Volume 12 Issue 4

Leukotriene Receptor Antagonist in Treating Allergic Rhinitis; Literature Review


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Abstract

A type 1 hypersensitivity disorder is Allergic rhinitis that affects the nasal mucosa and is described by frequent attacks of rhinorrhea and sneezing, nasal pruritus, and nasal congestion. It is the most regular disease stated in the ENT clinic and is generally controlled by nasal corticosteroids, vasoconstrictors, oral antihistamines, oral leukotriene receptor antagonists, or a medley of these agents. This study aimed to study the literature on the disease and to evaluate the effectiveness and safeness of leukotriene receptor antagonists compared with other therapeutic agents. We checked the PubMed database and searched for related articles toward the issue. We used the following Mesh words: Leukotriene receptor antagonists, rhinitis, allergic rhinitis, montelukast. The leukotriene (montelukast) receptor antagonist appears to play a restorative role in the treatment of patients with asthma and allergic rhinitis. However, compared with other agents, most current trials reported that montelukast provides greater effect in allergic rhinitis patients than placebo, especially nighttime symptoms, equal effect to antihistamine, and inferior to nasal corticosteroids. Additionally, montelukast, when combined with other agents, seems to provide a greater beneficial effect than monotherapy.


How to cite this article
Vancouver
Alzughaibi TK, Alhejaili RF, Ali AZ, Alfaifi AJ, Almaramhi HM, Alqifari AF, et al. Leukotriene Receptor Antagonist in Treating Allergic Rhinitis; Literature Review. J Biochem Technol. 2021;12(4):99-103. https://doi.org/10.51847/hg79JzKyou
APA
Alzughaibi, T. K., Alhejaili, R. F., Ali, A. Z., Alfaifi, A. J., Almaramhi, H. M., Alqifari, A. F., Alwthainani, A. S., Alkhamis, R. S., Aldosari, N. T., & Alshammari, B. A. (2021). Leukotriene Receptor Antagonist in Treating Allergic Rhinitis; Literature Review. Journal of Biochemical Technology, 12(4), 99-103. https://doi.org/10.51847/hg79JzKyou
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative