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2021 Volume 12 Issue 4

In-vivo Antioxidant Effects of the Orally Administered Paracetamol, Aqueous Extracts of Saliva triloba, and Origanum syriacum


Abstract

The plant extracts are found to be effective against oxidative stress. There are lots of reasons for increased oxidative stress in which environmental factors and life style play a big role. In this study the herbal extracts of Saliva triloba, and Origanum syriacum used to study antioxidant properties compared to paracetamol. A total of 27 volunteers were divided into 3 groups, 2 groups took 250 ml of aqueous extract of S. triloba, and O. syriacum for 5 days and 3rd group took paracetamol 500 mg, each tablet twice a day for five days. Blood specimens were collected before taking extract and one hour after taking the first dose at day one and one day after the last dose. Serum Total Antioxidant Status (TAS) and reduced glutathione (GSH), malondialdehyde (MDA) and Superoxide Dismutase (SOD) in RBCs were tested. The oral intake of aqueous extract of the plants for five days increased serum TAS and GSH in RBCs compared to zero time of intake. In addition, oral intake of aqueous extracts of Saliva triloba for five days increased significantly, P value ≤ 0.05 the activity of SOD in RBCs as compared to zero time of administration. The herbs extracts of Saliva triloba and Origanum syriacum have anti-oxidant property compared to paracetamol, so as medicinal herbs with antioxidant effects can inhibit produced oxidative effects.


How to cite this article
Vancouver
Alabdallat NG. In-vivo Antioxidant Effects of the Orally Administered Paracetamol, Aqueous Extracts of Saliva triloba, and Origanum syriacum . J Biochem Technol. 2021;12(4):19-22. https://doi.org/10.51847/X2h7Xdy40g
APA
Alabdallat, N. G. (2021). In-vivo Antioxidant Effects of the Orally Administered Paracetamol, Aqueous Extracts of Saliva triloba, and Origanum syriacum . Journal of Biochemical Technology, 12(4), 19-22. https://doi.org/10.51847/X2h7Xdy40g
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Deniz Publication on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal of Biochemical Technology provides a publication on all aspects of biochemistry, biotechnology & bioinformatics and applications in biology and medicine. Areas of high interest cover new advances in enzymatic and protein mechanisms; applied molecular genetics and biotechnology; computational biology, genomics and proteomics; metabolic & tissue engineering; medical, environmental, Pharmacy and pharmaceutical chemistry, food and agro-biotechnology.

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative