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2023 Volume 14 Issue 2

Immunology and Microbiology to the Article “SARS-CoV-2 Infection”


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Abstract

This study aims to identify the features of clinical and immunological signs accompanying pathological changes caused by COVID-19 in moderate and severe diseases. To identify complications of acute respiratory disease caused by SARS-CoV-2, detected at autopsy. Retrospective analysis of the results of immunological and microbiological studies of 20 patients with confirmed SARS-CoV-2 infection who were treated in clinics of the city of Sumy in 2020-2021: Group 1: 25.0% with severe disease (mean age 62.1±2.1 years); Group 2: 75.0% with mild or asymptomatic disease (43.0±0.9 years). Analysis of 20 autopsy reports and inpatient medical records for deceased patients for the period from December 2020 to June 2021. The main morphological, clinical, and immunological changes detected in both groups are described, the changes in the body for acute respiratory viral infection SARS-CoV-2 in mild and severe forms of the disease are analyzed. The results of autopsies in severe COVID-19 that resulted in death are presented. The rapid spread of SARS-CoV-2 is caused by the antigenic variability of viruses under the influence of immune factors in the body of previously infected people and is associated with defects in the organization of medical care in medical institutions of the region and Ukraine as a whole, as well as with underfunding of the medical sector and health care.


How to cite this article
Vancouver
Budko H, Ivakhniuk T, Sushchenko S, Kozyr N. Immunology and Microbiology to the Article “SARS-CoV-2 Infection”. J Biochem Technol. 2023;14(2):32-42. https://doi.org/10.51847/44bVI7Lvev
APA
Budko, H., Ivakhniuk, T., Sushchenko, S., & Kozyr, N. (2023). Immunology and Microbiology to the Article “SARS-CoV-2 Infection”. Journal of Biochemical Technology, 14(2), 32-42. https://doi.org/10.51847/44bVI7Lvev
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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a double-blind peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

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FOCUS AND SCOPE
Journal Of Biochemical Technology Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative