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2019 Volume 10 Issue 1

Histochemical Study of the Effect of Glycerol on the Kidney of Male Albino Rats Treated with Gum Arabic


Ohoud Abdullah Albeladi
Abstract

Kidney diseases are common health problems around the world and have different causes. Therefore, the study was based on glycerol because it is used extensively to determine the extent of the effect on the kidneys. Gum Arabic was chosen as a preventive treatment to reduce inflammation. The experiment was carried out on 70 male Albino rat, with a weight of 200-250 g. To verify kidney efficiency, pyramphenol blue dye was used to detect the level of proteins in the kidney. Also, a shif detector was used to explain the proportion of sugars in the kidney. The rats were divided into four groups; the first one was the standard (10): food and water were given only daily. The second group: treatment with glycerol for 4 weeks (20) with a dose of 10 ml / km. The third one: treated with glycerol for 8 weeks (20) at a dose of 10 ml / km. The fourth group: treatment with gum extract in the dose of 3 ml / km for 4 weeks (20). The serum was obtained to study the level of creatinine, and its increase was recorded in rats treated with glycerol and the low rate of treatment with Arabic gum. The results of the study of the kidneys in the groups treated with glycerol showed sharp changes in the cortex where there is enlargement and atrophy of some glomeruli, dissolution and dissociation in the capillaries of the capillaries and the broadening of the urinary cavity of the glomeruli. The color of the paramphenol blue and the shif is clearly shown as a result of the accumulation of proteins and sugars in the kidney. The Kidney failure and kidney dysfunction slight improvement was observed in the form of glomeruli and renal tubules, a lack of deformities in the nuclei and a decrease in hemorrhage between the tubes. The Arab gum treatment reduces the severity of kidney inflammation if used at the beginning of the discovery of inflammation.


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JOURNAL OF BIOCHEMICAL TECHNOLOGY
JOURNAL OF BIOCHEMICAL TECHNOLOGY
Journal of Biochemical Technology is a peer reviewed International Journal published by the Sevas Publishing on behalf of the Biochemical Technology Society, a Registered Charity Organization from India

AREA OF INTEREST
AREA OF INTEREST
Areas of high interest, cover new advances in enzymatic and protein mechanims; applied molecular genetics and biotechnology; genomics and proteomics; metabolic; medical, environmental, food and agro biotechnology.

FOCUS AND SCOPE
FOCUS AND SCOPE
Journal Of Biochemical Technology” Provides A Medium For The Rapid Publication Of Full-Length Articles, Mini-Reviews Of New And Emerging Products And Short Communications On All Aspects Of ...

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This journal provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Keywords include, Biochemical Research: Endo/exocytosis, Trafficking, Membrane Biology, Cell Migration, Cell-Matrix Organelle Biogenesis, Cytoskeleton Proteolysis, Cell Death, Cell Cycle, Cancer, Cell Growth/Death, Differentiation, Drug Targets, Gene Therapy, Models of Disease, Proteomics, Stem Cells, Bioenergetics, Mitochondria, Free Radicals, Redox Signaling, Ion Transport/Channels, Oxidative