The study was conducted based on the Moscow State Pedagogical University with the involvement of 126 students aged 17 to 21 years. Of these, 101 students suffered a coronavirus infection (experimental group). The control group consisted of 25 people who did not have COVID-19. The study included a questionnaire on the scale of asthenic condition, measurement of lung capacity, calculation of the Skibinsky index, determination of breath holding time, assessment of exercise tolerance, and cardiac rhythmography. Statistical data processing was carried out using the Microsoft Excel, STATISTICA 10 software package. Differences in the occurrence of deviations in the subjective and objective status of recovered and not ill students were noted. Most of the surveyed, who had asthenia, suffered from COVID-19 (85%). The recovered patients showed a significant decrease in the vital capacity of the lungs, and the presence of more pronounced shortness of breath in the six-minute walk test compared to the control group. According to the majority of the conducted tests, it was noted that the disease left fewer consequences for students who previously regularly went in for sports. To prevent the development and weakening of the manifestations of the post-COVID syndrome, all students should be strongly advised to increase the level of regular physical activity in any sport.