Introduction: Breast cancer is one of the most prevalent malignancies in the world and a major problem that cancer patients struggle with is the failure in timely and early diagnosis. The present study is an attempt to survey EDG PET/CT findings in breast cancer patients for the purpose of initial staging versus restaging and its impact on clinical management. Methodology: In this descriptive-analytical study all breast cancer patients referred to Masih Daneshvari Hospital for the purpose of initial staging or restaging were included. All patients’ medical record information including CT scan and MRI findings, FDG PET/CT results and treatment protocols were reviewed. Findings: The mean age of the patients was 52.73±11.90 years. The most common reason for patient referral was metastatic evaluation (43.1%) and least common reason was initial staging (5.2%). Interestingly extremities involvements were more frequently diagnosed on PET/CT (74.9%) comparing to the imaging modalities (41.6%). Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of PET/CT to detect lesions were 96.98%, 40.81%, 53.82%, 95%, 64.16% respectively. Conclusion: Using PET/CT imaging is a reliable method for evaluating breast cancer. This method is also helpful to direct the biopsy site and further treatment planning.
