Introduction and purpose: Cancer is the third leading cause of mortality after coronary disease and incidents. Breast cancer is a malignant proliferation of epithelial cells of the breast ducts or lobules. Breast cancer is one of the main problems of the health system for women in all countries, such as Iran. Annually, more than 1.3 million people are diagnosed with breast cancer in the world. The present study examined the effect of and the relationship between degree and stage of the tumor with neutrophil to lymphocyte ratio in patients for sooner diagnosis. Materials and methods: the sample was all female patients, 178 patients, with breast cancer aged 18-70 admitted to Hematologist Clinic from 2010 to 2015 for diagnosis and treatment. The initial CBC and the results of hormonal and respiratory analyses as well as the pathologic results of these patients were examined and analyzed and after studying the patients’ records, their information entered to Spss18.0 software and analyzed. Results: The results indicated a relationship between neutrophil to lymphocyte ratio with sickness stage. Discussion and conclusion: the overall results showed that with increase in the rate of tumor progression and its metastasis, NLR increases, but the degree of tumor or grade has no relationship with NLR.
