Evaluation of radioprotective efficacy of Ficus racemosa in Swiss albino mice exposed to electron beam radiation

The aim of this study was to evaluate the radioprotective potency of various doses (100, 200 and 400mg/kg b. wt) of ethanolic stem bark extract of Ficus racemosa (L.) on mice exposed to 6Gy electron beam radiation. Pre supplementation of Ficus racemosa for 15 days significantly reduced the malondialdehyde level in liver and was found to protect livers of irradiated mice from depletion of endogenous antioxidant enzymes like glutathione, GST, SOD, catalase and thiols. Pre supplementation also showed marked increase in WBC, spleen and thymus index. It also protected the liver, kidney and intestine from acute radiation effects, contributing to the over all radioprotective activity.