Background and Objective: The need for precautionary measures in specific work environments where employees spend a lot of daily work hours led to the study being conducted in the large petrochemical industry in order to investigate the factors enabling and inhibiting the physical activity of employees. Materials and Methods: This analytical study was conducted on 300 employees of Bandar Imam Petrochemical Complex in 2018. The inclusion criteria for entering the study were employees who had an employment action showing official employment, contractual employment, and short-term contractual employment. The instruments of this research were designed by the researcher and distributed among a random sample size of employees of various units of the complex. Data were analyzed using SPSS. Results: The mean score for variables the enabling factors, including security (2.19), facilities (2.72) and access to physical activity spaces in the workplace and living environment (2.42), as well as the score for the inhibiting factors, including environmental barriers (1.96), individual barriers (1.54) and social barriers (1.80), barriers related to the family of employees (1.90), were determined and analyzed comparatively. Discussion: The findings of the study showed that the enabling factors had a greater influence on the physical activity of the employees. Therefore, it is suggested that interfering barriers be studied and effective interventions for each of the variables be established and implemented.