Introduction: Postintubation sore throat is an inflammatory reaction following intratracheal intubation, which causes anxiety and stress for patients. Given the anti-inflammatory effects of rosemary extract, this substance seems to be able to prevent postintubation sore throat. Methodology: The present double-blind clinical trial was performed on 70 patients who were assigned to intervention and control groups based on the randomly permuted quadruple blocks. A sterile gauze impregnated with rosemary extract (for the intervention group) and a sterile gauze impregnated with normal saline (for the control group) was put at the patients’ pharynx. The status of postoperative sore throat was measured by the Visual Analogue Scale (VAS) and the data were statistically analyzed using chi-square and Fisher’s exact test at the significance level of 0.05. Results: The prevalence of sore throat in the intervention group (treated with rosemary extract) and the control group was 48.57±4.55 and 54.28±4.91, respectively. This indicated no significant difference between the two groups (p=0.6). In addition, there was no significant difference between the two groups after anesthesia. Discussion and Conclusion: Rosemary extract has been reported to be beneficial in most studies due to its anti-inflammatory compounds. However, administering this extract to the patients’ pharynx after intubation had no reducing effect on sore throat as a common postintubation complication.
