A growing number of research on management and diagnostic strategies in respiratory distress syndrome have been undertaken; nevertheless, there is no clear consensus on the prognosis among those patients. The goal of this systematic review was to consolidate current data on the management and diagnosis of patients with respiratory distress syndrome. The authors began by recognizing the important examination proof that spots light on the management and diagnosis of respiratory distress syndrome. We led electronic writing look in the accompanying data sets: Ovid Medline (2015 to present), Ovid Medline Daily Update, Ovid Medline in process and other non-filed references, Ovid Embase (2015 to present), The Cochrane Library (latest issue) and Web of Science. Just examinations in the English language will be incorporated. The precise selection was acted in close collaboration with a clinical examination curator. In all included studies the management was done at ICU and the diagnosis was done through chest x-ray and CT scans. The design was a retrospective study and prospective cohort study. The causes of ARDS varied among studies. Community-acquired pneumonia was the most common cause. One study included infants with ARDS. Other studies included ARDS in COVID-19 patients. The ICU stay length ranged from 11 to 21 days. The death occurred among several patients. ARDS management focuses primarily on supportive care, lung-protective ventilation, and reducing the type of iatrogenic lung injury, and extracorporeal life support is the last resort for patients who continue to deteriorate despite these supportive treatments.