Introduction: Thyroid disease affects 2-3% of pregnant women and is associated with undesirable pregnancy outcomes. Thyroid antibodies in euthyroid women are associated with a significant risk of forgetfulness, abortion, preterm birth, and postpartum maternal euthyroidism. Hence, present study was conducted to evaluate the different levels of TSH and Anti TPO in the two groups of giving birth pregnant women and pregnant women with aborted fetus. Methodology: This cross-sectional study was conducted comparatively between 2016 and 2017 years. A total of 156 pregnant women at gestational age of 8 to 14 weeks were divided into two groups of pregnant women who were giving birth and pregnant women with aborted fetus and their TSH and Anti TPO levels were measured and compared. Data on participants were collected and then were analyzed using SPSS, version 21, software. Results: The mean age of participants was 28.9 years. This study revealed that with increasing TSH, the frequency of abortion increased significantly (P = 0.012). It also revealed that with increasing TSH level, the frequency of pregnant women with Anti TPO was significantly higher than normal (P = 0.006). Results showed that frequency of abortion increased with increasing anti TPO (P = 0.00). Conclusion: Positive anti TPO Ab may result in abortion in the first trimester of pregnancy.
