Introduction: LDH and uric acid are two considerable markers in the new researches on the preeclampsia patients. The aim of this study was Comparison of the Level of Uric Acid and LDH in Mothers in Early and Late Preeclampsia and Determination of Its Association with the Severity of Preeclampsia. Method: In a descriptive-analytical study, 64 mothers with preeclampsia were studied in two early and late preeclampsia groups, groups was divided into individuals with severe or mild preeclampsia. While examining the demographic data, Hemato-biochemical tests were performed in order to examine the level of uric acid and LDH; the data analyzed by SPSS software version 20. Results: The mean age of the total patients was 29.40 ± 5.37 years. The mean of uric acid in the early group was 5.49 ± 1.43 and for late group was 4.63 ± 1.44, that was significantly higher in the early group (P <0.001). The mean LDH in the early group was 362.63 ± 262.29 and for the late group was 427.64 ± 174.59, that was significantly higher in the late group (P = 0.004). In addition, in both early and late groups, the mean LDH of the severe patients was significantly higher than the mild patients (P = 0.004). The correlation between the age of patients with their uric acid level in late patients showed a significant positive correlation (P = 0.015). Conclusion: uric acid in pregnant women with preeclampsia significantly increases, so that it is higher in early preeclampsia pregnant women than the late preeclampsia group; and it is higher in severe preeclampsia individuals than those with mild preeclampsia. In addition, LDH of late preeclampsia is more prevalent than tthe early preeclampsia, and it is significantly higher in severe cases compared to the mild patients.
