Introduction: Anterior nasal packing is a common method in nasal surgery. One of the complications that is debated today is about cardiovascular effects due to using nasal packing. Objective: This study aimed to evaluate some cardiac parameters in different groups to identify the safest way and use it in treatment to minimize cardiovascular complications. Method: In this clinical trial, 104 candidates for septoplasty were initially screened and 14 patients were excluded and 90 patients selected by block randomization. Blood pressure, heart rate and cardiac rhythm were monitored by different assessor for three time before surgery, then a classic septoplasty was done for all patients and after it patients were randomly divided into three groups: 1.without nasal packing2.with nasal packing.3.with nasal packing that had airway. Then, 24 hours after surgery, blood pressure and heart rate were monitored by 24-hour Holter. The monitoring results were interpreted by a cardiologist and the data were analyzed .Significance criterion of data was assumed as p-value ≤0.05. Results : Mean diastolic blood pressure after surgery in group 1-3was: 73.4±7.3 mmHg, 76.4±5.8 mmHg, 80.9±6 mmHg respectively and this criterion was lower in patients without nasal packing and showed a significant difference with patients that had nasal packing with airway (p=0.03). Mean heart rate after surgery in group 1-3was 71.8±11.3, 77.7±7.9, 79.1±6.7 respectively and the first group showed a significant difference with group(3) (p=0.043). Conclusion: This research showed that the use of anterior nasal packing with and without airway leads to cardiovascular changes such as increased diastolic blood pressure and heart rate. More studies should be conducted to create certain conclusion, so it is better that the use of nasal packing be considered on the balance of its risk and benefit.
